Mycobacterium tuberculosisrequires glyoxylate shunt and reverse methylcitrate cycle for lactate and pyruvate metabolism-Reference-Cited by-同舟云学术

Mycobacterium tuberculosisrequires glyoxylate shunt and reverse methylcitrate cycle for lactate and pyruvate metabolism

Published:2019-08-23 Issue:4 Volume:112 Page:1284-1307
ISSN:0950-382X
Container-title:Molecular Microbiology
language:en
Short-container-title:Mol Microbiol

Author:

Serafini Agnese¹,Tan Lendl²,Horswell Stuart³,Howell Steven⁴,Greenwood Daniel J.⁵,Hunt Deborah M.¹,Phan Minh‐Duy²,Schembri Mark²,Monteleone Mercedes⁶,Montague Christine R.⁷,Britton Warwick⁶,Garza‐Garcia Acely¹,Snijders Ambrosius P.⁴,VanderVen Brian⁷,Gutierrez Maximiliano G.⁵,West Nicholas P.²,Carvalho Luiz Pedro S.¹^ORCID

Affiliation:

1. Mycobacterial Metabolism and Antibiotic Research Laboratory The Francis Crick Institute 1 Midland RoadLondon NW1 1ATUK

2. School of Chemistry and Molecular Biosciences The University of Queensland Brisbane 4072Australia

3. Bioinformatics and Biostatistics Science Technology Platform The Francis Crick Institute 1 Midland RoadLondon NW1 1ATUK

4. Mass Spectrometry Science Technology Platform The Francis Crick Institute 1 Midland RoadLondon NW1 1ATUK

5. Host‐Pathogen Interactions in Tuberculosis Laboratory The Francis Crick Institute 1 Midland RoadLondon NW1 1ATUK

6. Mycobacterial Research Program Centenary Institute of Cancer Medicine and Cell Biology Camperdown NSW 2050Australia

7. Department of Microbiology and Immunology, College of Veterinary Medicine Cornell University Ithaca NY USA

Funder

Cancer Research UK

Medical Research Council

Wellcome Trust

Francis Crick Institute

Publisher

Wiley

Subject

Molecular Biology,Microbiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/mmi.14362

Reference74 articles.

1. 3-Nitropropionate, the toxic substance of Indigofera, is a suicide inactivator of succinate dehydrogenase

2. Genetic and metabolic regulation of Mycobacterium tuberculosis acid growth arrest

3. The anaplerotic node is essential for the intracellular survival of Mycobacterium tuberculosis

4. An Anaerobic-Type α-Ketoglutarate Ferredoxin Oxidoreductase Completes the Oxidative Tricarboxylic Acid Cycle of Mycobacterium tuberculosis

5. 13C Metabolic Flux Analysis Identifies an Unusual Route for Pyruvate Dissimilation in Mycobacteria which Requires Isocitrate Lyase and Carbon Dioxide Fixation

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