Urine assay for tenofovir to monitor adherence in real time to tenofovir disoproxil fumarate/emtricitabine as pre-exposure prophylaxis

Author:

Koenig HC12ORCID,Mounzer K12,Daughtridge GW3,Sloan CE3,Lalley-Chareczko L1,Moorthy GS45,Conyngham SC1,Zuppa AF45,Montaner LJ6,Tebas P2

Affiliation:

1. Philadelphia FIGHT; Philadelphia PA USA

2. Division of Infectious Diseases; Department of Medicine; Perelman School of Medicine at the University of Pennsylvania; Philadelphia PA USA

3. Perelman School of Medicine at the University of Pennsylvania; Philadelphia PA USA

4. Center for Clinical Pharmacology; The Children's Hospital of Philadelphia; Philadelphia PA USA

5. Department of Anesthesiology and Critical Care Medicine; The Children's Hospital of Philadelphia; Philadelphia PA USA

6. Wistar Institute; Philadelphia PA USA

Funder

National Institutes of Health

University of Pennsylvania Center for AIDS Research

Gilead Sciences

Publisher

Wiley

Subject

Pharmacology (medical),Infectious Diseases,Health Policy

Reference29 articles.

1. Preexposure chemoprophylaxis for HIV prevention in men who have sex with men;Grant;N Engl J Med,2010

2. Antiretroviral prophylaxis for HIV prevention in heterosexual men and women;Baeten;N Engl J Med,2012

3. Emtricitabine-tenofovir concentrations and pre-exposure prophylaxis efficacy in men who have sex with men;Anderson;Sci Transl Med,2012

4. Preexposure prophylaxis for the prevention of HIV infection in the united states - 2014 clinical practice guideline [homepage on the Internet] 2014 http://www.cdc.gov/hiv/pdf/prepguidelines2014.pdf

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