Novel highly potent OXE receptor antagonists with prolonged plasma lifetimes that are converted to active metabolites in vivo in monkeys-Reference-Cited by-同舟云学术

Novel highly potent OXE receptor antagonists with prolonged plasma lifetimes that are converted to active metabolites in vivo in monkeys

Published:2020-01 Issue:2 Volume:177 Page:388-401
ISSN:0007-1188
Container-title:British Journal of Pharmacology
language:en
Short-container-title:Br J Pharmacol

Author:

Ye Qiuji¹^ORCID,Chourey Shishir¹^ORCID,Reddy Chintam Nagendra¹,Wang Rui¹,Cossette Chantal²,Gravel Sylvie²,Slobodchikova Irina³,Vuckovic Dajana³^ORCID,Rokach Joshua¹^ORCID,Powell William S.²^ORCID

Affiliation:

1. Claude Pepper Institute and Department of ChemistryFlorida Institute of Technology Melbourne Florida

2. Meakins‐Christie Laboratories, Centre for Translational BiologyMcGill University Health Centre Montreal QC Canada

3. Department of Chemistry and Biochemistry and PERFORM CentreConcordia University Montreal QC Canada

Funder

Natural Sciences and Engineering Research Council of Canada

National Science Foundation

National Heart, Lung, and Blood Institute

American Asthma Foundation

Canadian Institutes of Health Research

Publisher

Wiley

Subject

Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bph.14874

Reference39 articles.

1. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: G protein-coupled receptors

2. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Enzymes

3. Update on leukotriene, lipoxin and oxoeicosanoid receptors: IUPHAR Review 7

4. In vivo α-hydroxylation of a 2-alkylindole antagonist of the OXE receptor for the eosinophil chemoattractant 5-oxo-6,8,11,14-eicosatetraenoic acid in monkeys

5. Novel Highly Potent and Metabolically Resistant Oxoeicosanoid (OXE) Receptor Antagonists That Block the Actions of the Granulocyte Chemoattractant 5-Oxo-6,8,11,14-Eicosatetraenoic Acid (5-oxo-ETE)

Cited by 11 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Biological Roles of 5-Oxo-6,8,11,14-Eicosatetraenoic Acid and the OXE Receptor in Allergic Diseases: Collegium Internationale Allergologicum Update 2024;International Archives of Allergy and Immunology;2024

2. Editorial: A year in review: discussions in cellular endocrinology;Frontiers in Endocrinology;2023-10-02

3. Concise Syntheses of Microsomal Metabolites of a Potent OXE (Oxoeicosanoid) Receptor Antagonist;Chemical and Pharmaceutical Bulletin;2023-07-01

4. Metabolism of anti-inflammatory OXE (oxoeicosanoid) receptor antagonists by nonhuman primates;European Journal of Pharmaceutical Sciences;2022-05

5. Targeting the OXE receptor with a selective antagonist inhibits allergen‐induced pulmonary inflammation in non‐human primates;British Journal of Pharmacology;2021-12-16