Metabolism of anti-inflammatory OXE (oxoeicosanoid) receptor antagonists by nonhuman primates-Reference-Cited by-同舟云学术

Metabolism of anti-inflammatory OXE (oxoeicosanoid) receptor antagonists by nonhuman primates

Published:2022-05 Issue: Volume:172 Page:106144
ISSN:0928-0987
Container-title:European Journal of Pharmaceutical Sciences
language:en
Short-container-title:European Journal of Pharmaceutical Sciences

Author:

Cossette Chantal,Chourey Shishir,Ye Qiuji^ORCID,Reddy Chintam Nagendra,Wang Rui,Poulet Sophie,Slobodchikova Irina,Vuckovic Dajana^ORCID,Rokach Joshua,Powell William S.^ORCID

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference31 articles.

1. A biased ligand for OXE-R uncouples Ga and Gbg signaling within a heterotrimer;Blättermann;Nat. Chem. Biol.,2012

2. In vivo a-hydroxylation of a 2-alkylindole antagonist of the OXE receptor for the eosinophil chemoattractant 5-oxo-6,8,11,14-eicosatetraenoic acid in monkeys;Chourey;Biochem. Pharmacol.,2017

3. Novel highly potent and metabolically resistant oxoeicosanoid (OXE) receptor antagonists that block the actions of the granulocyte chemoattractant 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE);Chourey;J. Med. Chem.,2018

4. Pharmacokinetics and metabolism of selective oxoeicosanoid (OXE) receptor antagonists and their effects on 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE)-induced granulocyte activation in monkeys;Cossette;J. Med. Chem.,2016

5. Targeting the oxoeicosanoid (OXE) receptor with a selective antagonist inhibits allergen-induced pulmonary inflammation in non-human primates;Cossette;Br. J. Pharmacol.,2022

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1. Concise Syntheses of Microsomal Metabolites of a Potent OXE (Oxoeicosanoid) Receptor Antagonist;Chemical and Pharmaceutical Bulletin;2023-07-01