Inhibition of phosphodiesterase-3 by levosimendan is sufficient to account for its inotropic effect in failing human heart-Reference-Cited by-同舟云学术

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Inhibition of phosphodiesterase-3 by levosimendan is sufficient to account for its inotropic effect in failing human heart

Published:2014-11-24 Issue:23 Volume:171 Page:5169-5181
ISSN:0007-1188
Container-title:British Journal of Pharmacology
language:en
Short-container-title:Br J Pharmacol

Author:

Ørstavik Ø¹²³,Ata S H¹²³,Riise J¹²³,Dahl C P²³⁴,Andersen G Ø³⁴,Levy F O¹²³,Skomedal T¹²³,Osnes J-B¹²³,Qvigstad E¹²³

Affiliation:

1. Department of Pharmacology; Faculty of Medicine; University of Oslo and Oslo University Hospital; Oslo Norway

2. K.G. Jebsen Cardiac Research Centre; Faculty of Medicine; University of Oslo; Oslo Norway

3. Center for Heart Failure Research; Faculty of Medicine; University of Oslo; Oslo Norway

4. Department of Cardiology; Oslo University Hospital; Oslo Norway

Publisher

Wiley

Subject

Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bph.12647/fullpdf

Reference39 articles.

1. 5-HT4-elicited positive inotropic response is mediated by cAMP and regulated by PDE3 in failing rat and human cardiac ventricles;Afzal;Br J Pharmacol,2008

2. Differential regulation of β2-adrenoceptor-mediated inotropic and lusitropic response by PDE3 and PDE4 in failing and non-failing rat cardiac ventricle;Afzal;Br J Pharmacol,2011

3. The Concise Guide to PHARMACOLOGY 2013/14: G Protein-Coupled Receptors;Alexander;Br J Pharmacol,2013a

4. The Concise Guide to PHARMACOLOGY 2013/14: Enzymes;Alexander;Br J Pharmacol,2013b

5. Site dependent bioavailability and metabolism of levosimendan in dogs;Antila;Eur J Pharm Sci,1999

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