Evidence that pregabalin reduces neuropathic pain by inhibiting the spinal release of glutamate
Author:
Publisher
Wiley
Subject
Cellular and Molecular Neuroscience,Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1471-4159.2010.06625.x/fullpdf
Reference49 articles.
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2. The increased trafficking of the calcium channel subunit alpha2delta-1 to presynaptic terminals in neuropathic pain is inhibited by the alpha2delta ligand pregabalin;Bauer;J. Neurosci.,2009
3. Gabapentin may inhibit synaptic transmission in the mouse spinal cord dorsal horn through a preferential block of P/Q-type Ca2+ channels;Bayer;Neuropharmacology,2004
4. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man;Bennett;Pain,1988
5. Calcium channel alpha2-delta type 1 subunit is the major binding protein for pregabalin in neocortex, hippocampus, amygdala, and spinal cord: an ex vivo autoradiographic study in alpha2-delta type 1 genetically modified mice;Bian;Brain Res.,2006
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