Irreversible blockade of sigma-1 receptors by haloperidol and its metabolites in guinea pig brain and SH-SY5Y human neuroblastoma cells

Author:

Cobos Enrique J.,Pozo Esperanza del,Baeyens José M.

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

Reference50 articles.

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3. 1-Methyl-4-phenylpyridinium-like neurotoxicity of a pyridinium metabolite derived from haloperidol: cell culture and neurotransmitter uptake studies;Bloomquist;J. Pharmacol. Exp. Ther.,1994

4. Acylation of σ receptors by Metaphit, an isothiocyanate derivative of phencyclidine;Bluth;Eur. J. Pharmacol.,1989

5. Metabolites of haloperidol display preferential activity at sigma receptors compared to dopamine D-2 receptors;Bowen;Eur. J. Pharmacol.,1990

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