Characterization of the Binding of N-Methyl-4-Phenylpyridine, the Toxic Metabolite of the Parkinsonian Neurotoxin N-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine, to Neuromelanin-Reference-Cited by-同舟云学术

Characterization of the Binding of N-Methyl-4-Phenylpyridine, the Toxic Metabolite of the Parkinsonian Neurotoxin N-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine, to Neuromelanin

Published:1987-02 Issue:2 Volume:48 Page:653-658
ISSN:0022-3042
Container-title:Journal of Neurochemistry
language:en
Short-container-title:J Neurochem

Author:

D'Amato Robert J.,Benham David F.,Snyder Solomon H.

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1471-4159.1987.tb04142.x/fullpdf

Reference28 articles.

1. Comparative Mössbauer and infrared analysis of iron-containing melanins

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3. A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

4. Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase

5. Selectivity of the Parkinsonian Neurotoxin MPTP: Toxic Metabolite MPP + Binds to Neuromelanin

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