Selectivity of the Parkinsonian Neurotoxin MPTP: Toxic Metabolite MPP + Binds to Neuromelanin-Reference-Cited by-同舟云学术

Selectivity of the Parkinsonian Neurotoxin MPTP: Toxic Metabolite MPP + Binds to Neuromelanin

Published:1986-02-28 Issue:4741 Volume:231 Page:987-989
ISSN:0036-8075
Container-title:Science
language:en
Short-container-title:Science

Author:

D'Amato Robert J.¹,Lipman Zoe P.¹,Snyder Solomon H.²

Affiliation:

1. Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 2I205.

2. Departments of Neuroscience, Pharmacology and Experimental Therapeutics, and Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference28 articles.

1. Bjorklund, A., Handbook of Chemcal Neuroanatomy 2: 89 (1984).

2. BURNS, R.S., THE NEUROTOXICITY OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE IN THE MONKEY AND MAN, CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES 11: 166 (1984).

3. Burns, R. S., Proceedings of the National Academy of Sciences of the United States of America 80: 4546 (1983).

4. CALNE, D.B., ETIOLOGY OF PARKINSONS-DISEASE, LANCET 2: 1457 (1983).

5. CASTAGNOLI, N, POTENTIAL BIOACTIVATION PATHWAYS FOR THE NEUROTOXIN 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP), LIFE SCIENCES 36: 225 (1985).

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