Passive immunization targeting pathological phospho-tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain
Author:
Publisher
Wiley
Subject
Cellular and Molecular Neuroscience,Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1471-4159.2011.07337.x/fullpdf
Reference55 articles.
1. Vaccination of Alzheimer’s model mice with Aβ derivative in alum adjuvant reduces Aβ burden without microhemorrhages;Asuni;Eur. J. Neurosci.,2006
2. Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements;Asuni;J. Neurosci.,2007
3. Non-Fc-mediated mechanisms are involved in clearance of amyloid-β in vivo by immunotherapy;Bacskai;J. Neurosci.,2002
4. Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease;Bard;Nat. Med.,2000
5. Lysosomal activation is a compensatory response against protein accumulation and associated synaptopathogenesis - An approach for slowing Alzheimer disease?;Bendiske;J. Neuropathol. Exp. Neurol.,2003
Cited by 273 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. A pentavalent peptide vaccine elicits Aβ and tau antibodies with prophylactic activity in an Alzheimer’s disease mouse model;Brain, Behavior, and Immunity;2024-11
2. Tau-Targeted Immunotherapy for Alzheimer's Disease: Insight into Clinical Trials;OBM Neurobiology;2024-08-07
3. Immunotherapies: A Treasure Trove of Alzheimer's Disease;Current Pharmaceutical Biotechnology;2024-07-19
4. Nasal tau immunotherapy clears intracellular tau pathology and improves cognitive functions in aged tauopathy mice;Science Translational Medicine;2024-07-03
5. Clearing truncated tau protein restores neuronal function and prevents microglia activation in tauopathy mice;2024-05-22
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3