Omalizumab normalizes the gene expression signature of lesional skin in patients with chronic spontaneous urticaria: A randomized, double‐blind, placebo‐controlled study-Reference-Cited by-同舟云学术

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Omalizumab normalizes the gene expression signature of lesional skin in patients with chronic spontaneous urticaria: A randomized, double‐blind, placebo‐controlled study

Published:2018-10-15 Issue:1 Volume:74 Page:141-151
ISSN:0105-4538
Container-title:Allergy
language:en
Short-container-title:Allergy

Author:

Metz Martin¹,Torene Rebecca²,Kaiser Sergio³,Beste Michael T.²,Staubach Petra⁴,Bauer Andrea⁵,Brehler Randolf⁶,Gericke Janine¹,Letzkus Martin³,Hartmann Nicole³,Erpenbeck Veit J.³,Maurer Marcus¹^ORCID

Affiliation:

1. Department of Dermatology and Allergy Charité – Universitätsmedizin Berlin Germany

2. Translational Medicine Novartis Cambridge Massachusetts

3. Translational Medicine Novartis Pharma AG Basel Switzerland

4. Department of Dermatology University Medicine Mainz Mainz Germany

5. Department of Dermatology University Allergy Center University Hospital Carl Gustav Carus Technical University Dresden Germany

6. Department of Dermatology University Hospital Muenster Muenster Germany

Funder

Novartis Pharma AG

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/all.13547

Reference40 articles.

2. Comparable actions of omalizumab on mast cells and basophils

3. Accelerated dissociation of IgE-FcεRI complexes by disruptive inhibitors actively desensitizes allergic effector cells

4. A randomized, placebo-controlled, dose-ranging study of single-dose omalizumab in patients with H1-antihistamine–refractory chronic idiopathic urticaria

5. Efficacy and safety of omalizumab in patients with chronic urticaria who exhibit IgE against thyroperoxidase

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1. The Effect of Placebo on Pruritus in Patients with Chronic Urticaria: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials;Clinical Drug Investigation;2024-09-06

2. Chronic Spontaneous Urticaria;Immunology and Allergy Clinics of North America;2024-08

3. Solar urticaria involves rapid mast cell STAT3 activation and neutrophil recruitment, with FcεRI as an upstream regulator;Journal of Allergy and Clinical Immunology;2024-05

4. Mapping the intellectual structure of the research of omalizumab in chronic spontaneous urticaria: A bibliometric analysis;Journal of Allergy and Clinical Immunology: Global;2024-05

5. Key genes and immune infiltration in chronic spontaneous urticaria: a study of bioinformatics and systems biology;Frontiers in Immunology;2023-11-15

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