Effects of exercise accumulation on plasma lipids and lipoproteins

Abstract

Debate exists as to whether improvements in some cardiometabolic risk factors following exercise training result more from the last session of, or from an accumulation of, exercise sessions. This study was designed to compare the effect of a single exercise session with 3 consecutive days of exercise on triglyceride (TG), high-density lipoprotein-cholesterol (HDL-C), and low-density lipoprotein-cholesterol (LDL-C). Twelve young adult (aged 22.5 ± 2.5 years), overweight (body mass index = 29.7 ± 4 kg·m–2), sedentary, black (n = 5) and white (n = 7) men (n = 6) and women (n = 6) completed, in random order, a single treadmill exercise session at 60% maximal oxygen uptake for 90 min (1EX), accumulated exercise sessions (same as for 1EX) for 3 consecutive days (3EX), and a control protocol (no exercise for 6 days). Plasma samples were collected from baseline through 24, 48, and 72 h postexercise. Significant treatment-by-time interactions (p < 0.05) existed in HDL-C and LDL-C. Postexercise responses of HDL-C differed at 48 h (1EX: –3.6, 3EX: + 3.7 mg·dL−1) and 72 h (1EX: –1.7, 3EX: + 3.2 mg·dL−1). LDL-C responses differed at 48 h (1EX: –16, 3EX: + 6 mg·dL−1). Although not statistically significant, TG concentrations decreased by 29% at 24 h after 3EX, compared with –7% after 1EX. An inverse relationship between baseline and postexercise reduction in TG was present with 3EX (r = –0.655; p < 0.05). In conclusion, 3EX increased HDL-C and decreased TG more than 1EX, while the decrease in LDL-C after 1EX was suppressed. Blood lipid panel changes may be due to more accumulated effects over time rather than just a result of the most recent exercise session.