Author:
MacGregor D. R.,Elliker P. R.
Abstract
Pseudomonas aeruginosa was adapted to grow on tryptone – glucose – yeast extract agar containing 2000 p.p.m. alkyldimethylethylbenzyl ammonium chloride (QAC-A). In germicidal trials these resistant cells could be made QAC-A sensitive by treatment with ethylenediaminetetraacetate. In Warburg studies lyophilized preparations of resistant strains were more sensitive to inhibition of substrate oxidation by QAC-A than the normal strain.It is postulated that quaternary ammonium germicide resistant strains of P. aeruginosa owe their resistance to their impermeability to QAC.
Publisher
Canadian Science Publishing
Subject
Genetics,Molecular Biology,Applied Microbiology and Biotechnology,General Medicine,Immunology,Microbiology
Cited by
69 articles.
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