Trityl chloride promoted the synthesis of 3-(2,6-diarylpyridin-4-yl)-1H-indoles and 2,4,6-triarylpyridines by in situ generation of trityl carbocation and anomeric based oxidation in neutral media-Reference-Cited by-同舟云学术

Trityl chloride promoted the synthesis of 3-(2,6-diarylpyridin-4-yl)-1H-indoles and 2,4,6-triarylpyridines by in situ generation of trityl carbocation and anomeric based oxidation in neutral media

Published:2016-07 Issue:7 Volume:94 Page:626-630
ISSN:0008-4042
Container-title:Canadian Journal of Chemistry
language:en
Short-container-title:Can. J. Chem.

Author:

Moosavi-Zare Ahmad Reza¹,Zolfigol Mohammad Ali²,Rezanejad Zahir²

Affiliation:

1. Department of Chemistry, Sayyed Jamaleddin Asadabadi University, Asadabad, 6541835583, Iran.

2. Faculty of Chemistry, Bu-Ali Sina University, Hamedan 6517838683, Iran.

Abstract

An efficient protocol for the synthesis of 2,4,6-triarylpyridines and 3-(2,6-diarylpyridin-4-yl)-1H-indoles by the one-pot pseudo four component condensation reaction of aldehydes with acetophenones and ammonium acetate in the presence of Ph3CCl under neutral and solvent-free conditions has been reported. Mechanistically, it is interesting that trityl chloride by in situ generation of trityl carbocation (Ph3C+) promotes the reaction. In this work, seven products have been reported for the first time.

Publisher

Canadian Science Publishing

Subject

Organic Chemistry,General Chemistry,Catalysis

Link

http://www.nrcresearchpress.com/doi/pdf/10.1139/cjc-2015-0629

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