Synthetic applications of the ruthenium-catalyzed hydrogenation via dynamic kinetic resolution

Author:

Ratovelomanana-Vidal Virginie,Genêt Jean-Pierre

Abstract

This review summarizes some recent work in the field of homogeneous ruthenium-catalyzed hydrogenation via dynamic kinetic resolution. The hydrogenation reaction of various α-substituted β-oxo esters using chiral ruthenium(II) catalysts is presented as well as the synthesis of some key intermediates of pharmaceutical interest.Key words: dynamic kinetic resolution, ruthenium, hydrogenation, α-substituted β-keto ester.

Publisher

Canadian Science Publishing

Subject

Organic Chemistry,General Chemistry,Catalysis

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