INHIBITION OF THE BACTERIOSTATIC ACTION OF LAURYLAMINE SACCHARINATE BY ORGANIC MATTER

Abstract

Laurylamine saccharinate has been tested for its bacteriostatic powers against 30 species of bacteria, namely, 6 Gram-positive micrococci, 12 Gram-positive and 12 Gram-negative 'rods'. The compound was used in concentrations of 0.0005, 0.001, and 0.005% in plain broth, broth with glycerol, and broth with glycerol and skim milk, these adjuncts representing progressively increasing amounts of organic matter. The Gram-negative bacteria were the most resistant. The bacteriostatic action of the laurylamine was progressively reduced by the organic matter. Staphylococcus aureus was not killed by 0.005% laurylamine in the medium containing skim milk. Media containing phenol were used as a measure of comparison, and similar effects of organic matter were observed. Agar also reduced the bacteriostatic power of the laurylamine.