CATALASE INHIBITION AS A POSSIBLE MECHANISM OF THE FUNGISTATIC ACTION OF SORBIC ACID

Author:

Troller John A.

Abstract

The fungistat, sorbic acid, has been shown to inhibit the activity of catalase. This inhibition is related to sorbic acid concentration, pH of the system, and length of time that the catalase was exposed to the acid. Both mold and mammalian catalases are inhibited, and mammalian catalase is shown to reverse the inhibitory effect of sorbic acid on molds. The rates of oxygen uptake by germinated and ungerminated spores have been compared in the presence and absence of sorbic acid, and it has been shown that sorbic acid exerts its most profound effect on spore germination. The possible significance of the auto-oxidative breakdown of sorbic acid is discussed.

Publisher

Canadian Science Publishing

Subject

Genetics,Molecular Biology,Applied Microbiology and Biotechnology,General Medicine,Immunology,Microbiology

Cited by 16 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Effect of sorbic acid and dual‐purpose inoculants on the fermentation quality and aerobic stability of high dry matter rice straw silage;Journal of Applied Microbiology;2020-10-22

2. Sorbic Acid;Kirk-Othmer Encyclopedia of Chemical Technology;2014-09-16

3. A new approach to problem of enzymatic catalysis based on excited state of proteins and Le Chatelier’s principle;Archives of Biochemistry and Biophysics;2007-08

4. Sorbic Acid;Kirk-Othmer Encyclopedia of Chemical Technology;2000-12-04

5. Preservation of personal care products;Preservation of Surfactant Formulations;1995

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