Eukaryotic elongation factor 2 kinase inhibitor, A484954 potentiates β-adrenergic receptor agonist-induced acute decrease in diastolic blood pressure in rats
Author:
Affiliation:
1. Laboratory of Veterinary Pharmacology, School of Veterinary Medicine, Kitasato University, Higashi 23 bancho 35-1, Towada, Aomori 034-8628, Japan
Publisher
Japanese Society of Veterinary Science
Subject
General Veterinary
Link
https://www.jstage.jst.go.jp/article/jvms/81/10/81_19-0425/_pdf
Reference17 articles.
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2. 2. Chen, Z., Gopalakrishnan, S. M., Bui, M. H., Soni, N. B., Warrior, U., Johnson, E. F., Donnelly, J. B. and Glaser, K. B. 2011. 1-Benzyl-3-cetyl-2-methylimidazolium iodide (NH125) induces phosphorylation of eukaryotic elongation factor-2 (eEF2): a cautionary note on the anticancer mechanism of an eEF2 kinase inhibitor. J. Biol. Chem. 286: 43951–43958.
3. 3. Kameshima, S., Kazama, K., Okada, M. and Yamawaki, H. 2015. Eukaryotic elongation factor 2 kinase mediates monocrotaline-induced pulmonary arterial hypertension via reactive oxygen species-dependent vascular remodeling. Am. J. Physiol. Heart Circ. Physiol. 308: H1298–H1305.
4. 4. Kameshima, S., Okada, M., Ikeda, S., Watanabe, Y. and Yamawaki, H. 2016. Coordination of changes in expression and phosphorylation of eukaryotic elongation factor 2 (eEF2) and eEF2 kinase in hypertrophied cardiomyocytes. Biochem. Biophys. Rep. 7: 218–224.
5. 5. Kameshima, S., Okada, M. and Yamawaki, H. 2019. Eukaryotic elongation factor 2 (eEF2) kinase/eEF2 plays protective roles against glucose deprivation-induced cell death in H9c2 cardiomyoblasts. Apoptosis 24: 359–368.
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