Eukaryotic elongation factor 2 kinase inhibitor, A484954 induced diuresis via nitric oxide production in spontaneously hypertensive rats
Author:
Affiliation:
1. Laboratory of Veterinary Pharmacology, School of Veterinary Medicine, Kitasato University, Aomori, Japan
Publisher
Japanese Society of Veterinary Science
Subject
General Veterinary
Link
https://www.jstage.jst.go.jp/article/jvms/85/12/85_23-0306/_pdf
Reference21 articles.
1. 1. Carey RM, Siragy HM, Gildea JJ, Keller SR. 2022. Angiotensin type-2 receptors: transducers of natriuresis in the renal proximal tubule. Int J Mol Sci 23: 2317.
2. 2. Chen Z, Gopalakrishnan SM, Bui MH, Soni NB, Warrior U, Johnson EF, Donnelly JB, Glaser KB. 2011. 1-Benzyl-3-cetyl-2-methylimidazolium iodide (NH125) induces phosphorylation of eukaryotic elongation factor-2 (eEF2): a cautionary note on the anticancer mechanism of an eEF2 kinase inhibitor. J Biol Chem 286: 43951–43958.
3. 3. Duarte JD, Cooper-DeHoff RM. 2010. Mechanisms for blood pressure lowering and metabolic effects of thiazide and thiazide-like diuretics. Expert Rev Cardiovasc Ther 8: 793–802.
4. 4. Hakam AC, Hussain T. 2006. Angiotensin II AT2 receptors inhibit proximal tubular Na +-K+-ATPase activity via a NO/cGMP-dependent pathway. Am J Physiol. Ren Physiol 290: 1430–1436.
5. 5. Kameshima S, Kazama K, Okada M, Yamawaki H. 2015. Eukaryotic elongation factor 2 kinase mediates monocrotaline-induced pulmonary arterial hypertension via reactive oxygen species-dependent vascular remodeling. Am J Physiol Hear Circ Physiol 308: 1298–1305.
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