Recombinant unpurified rETXH106P/ CTB-rETXY196E protects rabbits against Clostridium perfringens epsilon toxin
Author:
Affiliation:
1. Department of Bacterial Biologics, China Institute of Veterinary Drug Control, No. 8 Zhongguancun South Street, Beijing 100-081, China
2. Beijing Zhonghai Biotech Co., Ltd., No. 8 Zhongguancun South Street, Beijing 100-081, China
Publisher
Japanese Society of Veterinary Science
Subject
General Veterinary
Link
https://www.jstage.jst.go.jp/article/jvms/83/3/83_20-0385/_pdf
Reference13 articles.
1. 1. Alimolaei, M., Golchin, M. and Daneshvar, H. 2016. Oral immunization of mice against Clostridium perfringens epsilon toxin with a Lactobacillus casei vector vaccine expressing epsilon toxoid. Infect. Genet. Evol. 40: 282–287.
2. 2. Boberg, A., Gaunitz, S., Bråve, A., Wahren, B. and Carlin, N. 2008. Enhancement of epitope-specific cellular immune responses by immunization with HIV-1 peptides genetically conjugated to the B-subunit of recombinant cholera toxin. Vaccine 26: 5079–5082.
3. 3. Bokori-Brown, M., Hall, C. A., Vance, C., Fernandes da Costa, S. P., Savva, C. G., Naylor, C. E., Cole, A. R., Basak, A. K., Moss, D. S. and Titball, R. W. 2014. Clostridium perfringens epsilon toxin mutant Y30A-Y196A as a recombinant vaccine candidate against enterotoxemia. Vaccine 32: 2682–2687.
4. 4. Chandran, D., Naidu, S. S., Sugumar, P., Rani, G. S., Vijayan, S. P., Mathur, D., Garg, L. C. and Srinivasan, V. A. 2010. Development of a recombinant epsilon toxoid vaccine against enterotoxemia and its use as a combination vaccine with live attenuated sheep pox virus against enterotoxemia and sheep pox. Clin. Vaccine Immunol. 17: 1013–1016.
5. 5. Dorca-Arévalo, J., Pauillac, S., Díaz-Hidalgo, L., Martín-Satué, M., Popoff, M. R. and Blasi, J. 2014. Correlation between in vitro cytotoxicity and in vivo lethal activity in mice of epsilon toxin mutants from Clostridium perfringens. PLoS One 9: e102417.
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