Dynamics of Ku80 in Living Hamster Cells with DNA Double-Strand Breaks Induced by Chemotherapeutic Drugs

Author:

KOIKE Manabu1,KOIKE Aki1,SUGASAWA Jun1,TOYOOKA Tatsushi2,IBUKI Yuko2

Affiliation:

1. DNA Repair Gene Res., National Institute of Radiological Sciences

2. Laboratory of Radiation Biology, Graduate School of Nutritional and Environmental Sciences, University of Shizuoka

Publisher

Japanese Society of Veterinary Science

Subject

General Veterinary

Reference36 articles.

1. 1. Banath, J. P. and Olive, P. L. 2003. Expression of phosphorylated histone H2AX as a surrogate of cell killing by drugs that create DNA double-strand breaks. Cancer Res. 63: 4347-4350.

2. 2. Belenkov, A. I., Paiemen, J. P., Panasci, L. C., Monia, B. P. and Chow, T. Y. 2002. An antisense oligonucleotide targeted to human Ku86 messenger RNA sensitizes M059K malignant glioma cells to ionizing radiation, bleomycin, and etoposide but not DNA cross-linking agents. Cancer Res. 62: 5888-5896.

3. Genomic Instability in Mice Lacking Histone H2AX

4. Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks

5. The life and death of DNA-PK

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