Reference data of clinical chemistry, haematology and blood coagulation parameters in juvenile cynomolgus monkeys (Macaca fascicularis)

Abstract

Juvenile cynomolgus monkeys are valuable models for studying human diseases. Reference data of clinical chemistry, haematology and blood coagulation parameters of juvenile cynomolgus monkeys are very important for clinical diagnosis and conducting research. In this study, 72 blood samples (obtained from 35 males and 37 females) and 20 blood samples (obtained from 10 males and 10 females) were used to determine normal data of clinical serum chemistry, haematological profiles and normal blood coagulation parameters in juvenile cynomolgus monkeys. Seventeen markers of clinical serum chemistry, twenty-nine markers of haematology and two parameters of blood coagulation were analysed. These data may provide valuable information for veterinarians and investigators using juvenile cynomolgus monkeys in research on disease treatment and in experimental studies.