Author:
Babula P.,Šupálková V.,Adam V.,Havel L.,Beklová M.,Sladký Z.,Kizek R.
Abstract
The mechanism of cisplatin effect has been well examined in in vitro models of malignant cell lines, but has never been studied on plant cell lines. When plant cell suspension culture of <i>Nicotiana tabacum</i> BY-2 was treated with cisplatin a decrease of viability with its increasing concentration was observed as well as the mitotic index. The structure of nuclei has also been changed in dependence on cisplatin concentration.
Publisher
Czech Academy of Agricultural Sciences
Cited by
10 articles.
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