Proteolysis of Chimeric β-Amyloid Precursor Proteins Containing the Notch Transmembrane Domain Yields Amyloid β-like Peptides
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference43 articles.
1. Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein
2. Total inactivation of γ–secretase activity in presenilin-deficient embryonic stem cells
3. Presenilins are required for γ-secretase cleavage of β-APP and transmembrane cleavage of Notch-1
4. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity
5. The Transmembrane Aspartates in Presenilin 1 and 2 Are Obligatory for γ-Secretase Activity and Amyloid β-Protein Generation
Cited by 28 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Substrate recruitment by γ-secretase;Seminars in Cell & Developmental Biology;2020-09
2. Substrate determinants in the C99 juxtamembrane domains differentially affect γ-secretase cleavage specificity and modulator pharmacology;Journal of Neurochemistry;2013-01-18
3. The Effects of Transmembrane Sequence and Dimerization on Cleavage of the p75 Neurotrophin Receptor by γ-Secretase;Journal of Biological Chemistry;2012-12
4. Substrate Sequence Influences γ-Secretase Modulator Activity, Role of the Transmembrane Domain of the Amyloid Precursor Protein;Journal of Biological Chemistry;2011-11
5. Regulated intramembrane proteolysis - lessons from amyloid precursor protein processing;Journal of Neurochemistry;2011-04-14
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3