Structures of human cytochrome P450 1A1 with bergamottin and erlotinib reveal active-site modifications for binding of diverse ligands
Author:
Funder
HHS | NIH | National Institute of General Medical Sciences (NIGMS)
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference47 articles.
1. Contributions of human enzymes in carcinogen metabolism;Rendic;Chem. Res. Toxicol,2012
2. Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cytochromes P450 1A1 and 1B1;Shimada;Cancer Sci,2004
3. Mechanism-based inhibition of human cytochrome P450 1A1 by rhapontigenin;Chun;Drug Metab. Dispos,2001
4. Expression profile of CYP1A1 and CYP1B1 enzymes in colon and bladder tumors;Androutsopoulos;PLoS One,2013
5. Antitumor activity of a duocarmycin analogue rationalized to be metabolically activated by cytochrome P450 1A1 in human transitional cell carcinoma of the bladder;Sutherland;Mol. Cancer Ther,2013
Cited by 40 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Effects of some flavor enhancer food additives on expression of cancer-related genes in MCF-7 and MCF-12A cells;Cogent Food & Agriculture;2023-10-24
2. Hydration and Structural Adaptations of the Human CYP1A1, CYP1A2, and CYP1B1 Active Sites by Molecular Dynamics Simulations;International Journal of Molecular Sciences;2023-07-14
3. Key regulators in the architecture of substrate access/egress channels in mammalian cytochromes P450 governing flexibility in substrate oxyfunctionalization;Journal of Inorganic Biochemistry;2023-04
4. Melatonin Activation by Cytochrome P450 Isozymes: How Does CYP1A2 Compare to CYP1A1?;International Journal of Molecular Sciences;2023-02-11
5. Functions of the aryl hydrocarbon receptor (AHR) beyond the canonical AHR/ARNT signaling pathway;Biochemical Pharmacology;2023-02
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3