Insulin Activates RSK (p90 Ribosomal S6 Kinase) to Trigger a New Negative Feedback Loop That Regulates Insulin Signaling for Glucose Metabolism
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference50 articles.
1. Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein;Sun;Nature,1991
2. Molecular mechanisms of insulin resistance: serine phosphorylation of insulin receptor substrate-1 and increased expression of p85α: the two sides of a coin;Draznin;Diabetes,2006
3. Positive and negative regulation of insulin signaling through IRS-1 phosphorylation;Gual;Biochimie,2005
4. Amino acid and insulin signaling via the mTOR/p70 S6 kinase pathway. A negative feedback mechanism leading to insulin resistance in skeletal muscle cells;Tremblay;J. Biol. Chem,2001
5. S6K directly phosphorylates IRS-1 on Ser-270 to promote insulin resistance in response to TNF-α signaling through IKK2;Zhang;J. Biol. Chem,2008
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