A New Class of Allosteric HIV-1 Integrase Inhibitors Identified by Crystallographic Fragment Screening of the Catalytic Core Domain-Reference-Cited by-同舟云学术

A New Class of Allosteric HIV-1 Integrase Inhibitors Identified by Crystallographic Fragment Screening of the Catalytic Core Domain

Published:2016-11 Issue:45 Volume:291 Page:23569-23577
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Patel Disha,Antwi Janet,Koneru Pratibha C.,Serrao Erik,Forli Stefano,Kessl Jacques J.,Feng Lei,Deng Nanjie,Levy Ronald M.,Fuchs James R.,Olson Arthur J.,Engelman Alan N.,Bauman Joseph D.,Kvaratskhelia Mamuka,Arnold Eddy

Funder

National Institutes of Health

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference64 articles.

1. Retroviral integrase structure and dna recombination mechanism;Engelman;Microbiol. Spectr,2014

2. HIV-1 integrase multimerization as a therapeutic target;Feng;Curr. Top. Microbiol. Immunol,2015

3. Integrase illuminated;Cherepanov;EMBO Rep,2010

4. Structural biology of retroviral DNA integration;Li;Virology,2011

5. Structural insights into the retroviral DNA integration apparatus;Cherepanov;Curr. Opin. Struct. Biol,2011

Cited by 21 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Oligomeric HIV-1 Integrase Structures Reveal Functional Plasticity for Intasome Assembly and RNA Binding;2024-01-27

2. The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir;2024-01-26

3. Halo Library, a Tool for Rapid Identification of Ligand Binding Sites on Proteins Using Crystallographic Fragment Screening;Journal of Medicinal Chemistry;2023-04-28

4. Structure of a HIV-1 IN-Allosteric inhibitor complex at 2.93 Å resolution: Routes to inhibitor optimization;PLOS Pathogens;2023-03-03

5. The Halo Library, a Tool for Rapid Identification of Ligand Binding Sites on Proteins Using Crystallographic Fragment Screening;2022-10-17