Presenilin 1 and Presenilin 2 Have Differential Effects on the Stability and Maturation of Nicastrin in Mammalian Brain-Reference-Cited by-同舟云学术

Presenilin 1 and Presenilin 2 Have Differential Effects on the Stability and Maturation of Nicastrin in Mammalian Brain

Published:2003-05 Issue:22 Volume:278 Page:19974-19979
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Chen Fusheng,Tandon Anurag,Sanjo Nobuo,Gu Yong-Jun,Hasegawa Hiroshi,Arawaka Shigeki,Lee Frank J.S.,Ruan Xueying,Mastrangelo Peter,Erdebil Serap,Wang Linda,Westaway David,Mount Howard T.J.,Yankner Bruce,Fraser Paul E.,George-Hyslop Peter St

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference26 articles.

1. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

2. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

3. Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and βAPP processing

4. A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain

5. Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

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1. Presenilin Deficiency Results in Cellular Cholesterol Accumulation by Impairment of Protein Glycosylation and NPC1 Function;International Journal of Molecular Sciences;2024-05-16

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3. Quantitative Comparison of Presenilin Protein Expression Reveals Greater Activity of PS2-γ-Secretase;2023-05-10

4. Nicastrin Deficiency Induces Tyrosinase-Dependent Depigmentation and Skin Inflammation;Journal of Investigative Dermatology;2020-02

5. Presenilin 1 and Presenilin 2 Target γ-Secretase Complexes to Distinct Cellular Compartments;Journal of Biological Chemistry;2016-06