Suppressor Mutations for Presenilin 1 Familial Alzheimer Disease Mutants Modulate γ-Secretase Activities
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference57 articles.
1. Alzheimer disease;Selkoe;Cold Spring Harbor Perspect. Biol,2011
2. The presenilin hypothesis of Alzheimer disease: evidence for a loss-of-function pathogenic mechanism;Shen;Proc. Natl. Acad. Sci. U.S.A,2007
3. Loss-of-function presenilin mutations in Alzheimer disease;De Strooper;EMBO Rep,2007
4. When loss is gain: reduced presenilin proteolytic function leads to increased Aβ42/Aβ40;Wolfe;EMBO Rep,2007
5. Molecular mechanism of intramembrane proteolysis by γ-secretase;Tomita;J. Biochem,2014
Cited by 16 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Alzheimer’s Disease: Significant Benefit from the Yeast-Based Models;International Journal of Molecular Sciences;2023-06-06
2. The human RAP1 and GFAPɛ proteins increase γ-secretase activity in a yeast model system;G3: Genes, Genomes, Genetics;2023-03-17
3. Specific Mutations near the Amyloid Precursor Protein Cleavage Site Increase γ-Secretase Sensitivity and Modulate Amyloid-β Production;International Journal of Molecular Sciences;2023-02-16
4. Curcumin Analogues as Promissory Compounds for Inhibition of β-Secretase, γ-Secretase and GSK-3β Implicated at Alzheimer Disease: In Silico Study;Biomedical and Pharmacology Journal;2022-03-31
5. Presenilin Is Essential for ApoE Secretion, a Novel Role of Presenilin Involved in Alzheimer's Disease Pathogenesis;The Journal of Neuroscience;2022-01-05
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3