Design of a Long Acting Peptide Functioning as Both a Glucagon-like Peptide-1 Receptor Agonist and a Glucagon Receptor Antagonist-Reference-Cited by-同舟云学术

Design of a Long Acting Peptide Functioning as Both a Glucagon-like Peptide-1 Receptor Agonist and a Glucagon Receptor Antagonist

Published:2006-05 Issue:18 Volume:281 Page:12506-12515
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Pan Clark Q.,Buxton Joanne M.,Yung Stephanie L.,Tom Irene,Yang Ling,Chen Hongxing,MacDougall Margit,Bell Andrea,Claus Thomas H.,Clairmont Kevin B.,Whelan James P.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference45 articles.

1. International Union of Pharmacology. XXXV. The Glucagon Receptor Family

2. Expression cloning and signaling properties of the rat glucagon receptor

3. Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1.

4. Glucagon and glucagon-like peptide 1: selective receptor recognition via distinct peptide epitopes.

5. Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells.

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