Metabolic effects of combined glucagon receptor antagonism and glucagon-like peptide-1 receptor agonism in high fat fed mice

Author:

Franklin Zara J.,Lafferty Ryan A.,Flatt Peter R.,McShane Laura M.,O'Harte Finbarr P.M.,Irwin Nigel

Publisher

Elsevier BV

Subject

General Medicine,Biochemistry

Reference56 articles.

1. Effects of a novel glucagon receptor antagonist (Bay 27–9955) on glucagon-stimulated glucose production in humans;Petersen;Diabetologia,2001

2. The glucagon receptor is involved in mediating the body weight-lowering effects of oxyntomodulin;Kosinski;Obesity,2012

3. Oxyntomodulin analogue increases energy expenditure via the glucagon receptor;Scott;Peptides,2018

4. IBI362 (LY3305677), a weekly-dose GLP-1 and glucagon receptor dual agonist, in Chinese adults with overweight or obesity: a randomised, placebo-controlled, multiple ascending dose phase 1b study;Ji;EClin. Med.,2021

5. Proglucagon-derived peptides as therapeutics;Lafferty;Front. Endocrinol.,2021

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