Mapping the Binding Site of the Inhibitor Tariquidar That Stabilizes the First Transmembrane Domain of P-glycoprotein
Author:
Funder
Canadian Institutes of Health Research
Cystic Fibrosis Canada
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference69 articles.
1. Mammalian abc transporters in health and disease;Borst;Annu. Rev. Biochem,2002
2. Tariquidar inhibits P-glycoprotein drug efflux but activates ATPase activity by blocking transition to an open conformation;Loo;Biochem. Pharmacol,2014
3. A pilot study to assess the efficacy of tariquidar to inhibit P-glycoprotein at the human blood-brain barrier with (R)-11C-verapamil and PET;Wagner;J. Nucl. Med,2009
4. The “specific” P-glycoprotein inhibitor tariquidar is also a substrate and an inhibitor for breast cancer resistance protein (BCRP/ABCG2);Kannan;ACS Chem. Neurosci,2011
5. Correction of defective protein kinesis of human P-glycoprotein mutants by substrates and modulators;Loo;J. Biol. Chem,1997
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