Nevirapine Resistance Mutation at Codon 181 of the HIV-1 Reverse Transcriptase Confers Stavudine Resistance by Increasing Nucleotide Substrate Discrimination and Phosphorolytic Activity-Reference-Cited by-同舟云学术

Nevirapine Resistance Mutation at Codon 181 of the HIV-1 Reverse Transcriptase Confers Stavudine Resistance by Increasing Nucleotide Substrate Discrimination and Phosphorolytic Activity

Published:2003-05 Issue:18 Volume:278 Page:15469-15472
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Blanca Giuseppina,Baldanti Fausto,Paolucci Stefania,Skoblov Alexander Yu,Victorova Lyubov,Hübscher Ulrich,Gerna Giuseppe,Spadari Silvio,Maga Giovanni

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference11 articles.

1. Nucleoside Reverse Transcriptase Inhibitor Resistance

2. Resistance to nevirapine of HIV-1 reverse transcriptase mutants: loss of stabilizing interactions and thermodynamic or steric barriers are induced by different single amino acid substitutions

3. Combinations Against Combinations: Associations of Anti-HIV 1 Reverse Transcriptase Drugs Challenged by Constellations of Drug Resistance Mutations

4. Molecular mechanisms of HIV-1 resistance to nucleoside reverse transcriptase inhibitors (NRTIs)

5. Multidrug-resistant human immunodeficiency virus type 1 strains resulting from combination antiretroviral therapy

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