NPC intracellular cholesterol transporter 1 (NPC1)-mediated cholesterol export from lysosomes
Author:
Funder
HHS | NIH | National Heart, Lung, and Blood Institute
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference32 articles.
1. A receptor-mediated pathway for cholesterol homeostasis;Brown;Science,1986
2. Structure of a cholesterol-binding protein deficient in Niemann-Pick type C2 disease;Friedland;Proc. Natl. Acad. Sci. U.S.A,2003
3. Structural basis of sterol binding by NPC2, a lysosomal protein deficient in Niemann-Pick type C2 disease;Xu;J. Biol. Chem,2007
4. Mechanism of cholesterol transfer from the Niemann-Pick type C2 protein to model membranes supports a role in lysosomal cholesterol transport;Cheruku;J. Biol. Chem,2006
5. NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes;Infante;Proc. Natl. Acad. Sci. U.S.A,2008
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