Trypanosoma brucei Thymidine Kinase Is Tandem Protein Consisting of Two Homologous Parts, Which Together Enable Efficient Substrate Binding
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
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1. Giardia intestinalisdeoxyadenosine kinase has a unique tetrameric structure that enables high substrate affinity and makes the parasite sensitive to deoxyadenosine analogues;2023-12-18
2. Integrated spectroscopic and MD simulation approach to decipher the effect of pH on the structure function of Staphylococcus aureus thymidine kinase;Journal of Biomolecular Structure and Dynamics;2023-12-15
3. Targeting the nucleotide metabolism of Trypanosoma brucei and other trypanosomatids;FEMS Microbiology Reviews;2023-05
4. Giardia intestinalis thymidine kinase is a high-affinity enzyme crucial for DNA synthesis and an exploitable target for drug discovery;Journal of Biological Chemistry;2022-06
5. A Mitochondrial Orthologue of the dNTP Triphosphohydrolase SAMHD1 Is Essential and Controls Pyrimidine Homeostasis in Trypanosoma brucei;ACS Infectious Diseases;2021-01-08
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