A Mitochondrial Orthologue of the dNTP Triphosphohydrolase SAMHD1 Is Essential and Controls Pyrimidine Homeostasis in Trypanosoma brucei-Reference-Cited by-同舟云学术

A Mitochondrial Orthologue of the dNTP Triphosphohydrolase SAMHD1 Is Essential and Controls Pyrimidine Homeostasis in Trypanosoma brucei

Published:2021-01-08 Issue:2 Volume:7 Page:318-332
ISSN:2373-8227
Container-title:ACS Infectious Diseases
language:en
Short-container-title:ACS Infect. Dis.

Author:

Yagüe-Capilla Miriam¹,Castillo-Acosta Víctor M.¹,Bosch-Navarrete Cristina¹,Ruiz-Pérez Luis Miguel¹,González-Pacanowska Dolores¹^ORCID

Affiliation:

1. Instituto de Parasitología y Biomedicina “López-Neyra”, Consejo Superior de Investigaciones Científicas, Parque Tecnológico de Ciencias de la Salud, Armilla (Granada) 18016, Spain

Funder

Junta de Andaluc??a

Ministerio de Ciencia e Innovaci??n

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

Link

https://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.0c00551

Reference62 articles.

1. WHO. (2019) Trypanosomiasis, human African (sleeping sickness). https://www.who.int/news-room/fact-sheets/detail/trypanosomiasis-human-african-(sleeping-sickness) (accessed 2020-02-14).

2. Regulation by degradation, a cellular defense against deoxyribonucleotide pool imbalances

3. Regulation of mammalian nucleotide metabolism and biosynthesis

4. INTERACTIONS BETWEEN DEOXYRIBONUCLEOTIDE AND DNA SYNTHESIS

5. Pyrimidine Biosynthesis Is Not an Essential Function for Trypanosoma brucei Bloodstream Forms

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