Affiliation:
1. Hong Kong Baptist University
Abstract
A targeted imaging system has been developed for applications requiring recording from stationary samples at high spatiotemporal resolutions. It works by illuminating regions of interest in rapid sequence, and recording the signal from the whole field of view onto a single photodetector. It can be implemented at low cost on an existing microscope without compromising existing functionality. The system is characterized in terms of speed, spatial resolution, and tissue penetration depth, before being used to record individual action potentials from ASAP-3 expressing neurons in an ex vivo mouse brain slice preparation.
Funder
EPSRC Centre for Doctoral Training in Neurotechnology
Engineering and Physical Sciences Research Council
Biotechnology and Biological Sciences Research Council
Wellcome Trust
Cancer Research UK
Royal Society
Chan Zuckerberg Initiative
Imperial College Excellence Fund for Frontier Research
RIKEN
National Institutes of Health
Subject
Atomic and Molecular Physics, and Optics,Biotechnology
Cited by
1 articles.
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