A simple, rapid, economical, and practical method for the determination of efavirenz in plasma of Chinese AIDS patients by reverse phase high-performance liquid chromatography with ultraviolet detector
Author:
Affiliation:
1. Department of Infectious Diseases, Shanghai Public Health Clinical Center
2. Department of Pharmacy, Shanghai Public Health Clinical Center
3. Department of Clinical Pharmacy and Pharmaceutical Administration, School of Pharmacy, Fudan University
Publisher
International Research and Cooperation Association for Bio & Socio-Sciences Advancement (IRCA-BSSA)
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine,Health (social science)
Link
https://www.jstage.jst.go.jp/article/bst/8/4/8_2014.01002/_pdf
Reference56 articles.
1. 1. Bock P, Fatti G, Grimwood A. Comparing the effectiveness of efavirenz and nevirapine for first-line antiretroviral therapy in a South African multicentre cohort. Int Health. 2013; 5:132-138.
2. 2. Ward BA, Gorski JC, Jones DR, Hall SD, Flockhart DA, Desta Z.Gorski JC, Jones DR. The cytochrome P4502B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: Implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity. J Pharmacol Exp Ther. 2003; 306:287-300.
3. 3. Stahle L, Moberg L, Svensson JO, Sonnerborg A. Efavirenz plasma concentrations in HIV-infected patients - Inter- and intraindividual variability and clinical effects. Ther Drug Monit. 2004; 26:267-270.
4. 4. Aurpibul L, Chotirosniramit N, Sugandhavesa P, Kosashunhanan N, Thetket S, Supindham T, Piyamongkol W, Supparatpinyo K. Correlation of CYP2B6-516 G>T Polymorphism with Plasma Efavirenz Concentration and Depression in HIV-Infected Adults in Northern Thailand. Curr HIV Res. 2012; 10:653-660.
5. 5. Desta Z, Saussele T, Ward B, Blievernicht J, Li L, Klein K, Flockhart D, Zanger UM. Impact of CYP2B6 polymorphism on hepatic efavirenz metabolism in vitro. Pharmacogenomics. 2007; 8:547-558.
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