A case report of basosquamous carcinoma of thigh – An unusual location

Abstract

Basosquamous cell carcinoma (BSC), also known as metatypical carcinoma, is an uncommon form of basal cell carcinoma (BCC) that is thought to be aggressive and more likely to spread to other parts of the body. The head-and-neck area is where it often first manifests itself. BSC is an uncommon tumor with diverse forms and unpredictable symptoms. Our case is a 75-year-old male with a nonhealing ulcer on his right thigh for 4–5 years. We received a biopsy from the margins, which revealed basosquamous carcinoma, which was confirmed by immunohistochemistry. The highly aggressive nature of the tumor, the higher incidence of recurrence, and the possibility of metastasis make an early diagnosis of BSC crucial which is differentiating it with BCC, in which the low risk of metastasis and recurrences is there, minimal risks are observed in limbs far from the cephalic region. Due to their clinical similarities, it is hard to distinguish between BSC and BCC clinically. Histopathology could aid in prompt diagnosis and precise treatment. An immunohistochemical examination might yield additional information for a more precise diagnosis. Here, we describe a rare case of BSC presented as unusually located ulcer on the thigh. The following core competencies are addressed in this article: Medical knowledge, Patient care and procedural skills, Systems-based practice.