Author:
Ciążyńska Magdalena,Sławińska Martyna,Kamińska-Winciorek Grażyna,Lange Dariusz,Lewandowski Bogumił,Reich Adam,Pabianek Marta,Szczepaniak Katarzyna,Hankiewicz Adam,Ułańska Małgorzata,Morawiec Jan,Błasińska-Morawiec Maria,Morawiec Zbigniew,Piekarski Janusz,Brodowski Robert,Zaryczańska Anna,Sobjanek Michał,Owczarek Witold,Słowińska Monika,Wróbel Katarzyna,Bieniek Andrzej,Woźniacka Anna,Skibińska Małgorzata,Narbutt Joanna,Niemczyk Wojciech,Ciążyński Karol,Lesiak Aleksandra
Abstract
Abstract
Basosquamous carcinoma (BSC) is a rare non-melanoma skin cancer that shares the characteristic features of both basal and squamous cell carcinomas (BCC, SCC). Our research enables better characterization of BSC in comparison to high-risk subtypes of BCC and SCC. Paper includes a retrospective analysis of BSC cases regarding sex, age, number of tumors and anatomical distribution in comparison to BCC and SCC evaluating the differences and defining the implications. Histologically confirmed carcinomas recorded between 1999 and 2019 were studied. 181 diagnosed BSC cases were identified, making this study the largest cohorts of BSC patients reported worldwide. Most cases were reported on head and neck. Analysis of facial anatomic distribution shows that most commonly affected sites were the nose (43%) and the cheek (25%). The age at excision of metatypical BCC was higher than those of low-risk BCC (P < 0.05), however similar to high-risk BCC (P = 0.20). We revisited that the concept of BSC is the most similar to high-risk subtypes of BCC. Patients with diagnosed BSC have higher risk of second nonmelanoma skin cancer. Therefore, the frequency of follow-up examination should be adjusted to the individual risk of another skin cancer.
Funder
Uniwersytet Medyczny w Lodzi
National Centre of Science
Publisher
Springer Science and Business Media LLC
Reference33 articles.
1. Apalla, Z., Lallas, A., Sotiriou, E., Lazaridou, E. & Ioannides, D. Epidemiological trends in skin cancer. Dermatol. Pract. Concept 7, 1–6 (2017).
2. Dacosta Byfield, S., Chen, D., Yim, Y. M. & Reyes, C. Age distribution of patients with advanced non-melanoma skin cancer in the United States. Arch. Dermatol. Res. 305, 845–850 (2013).
3. Katalinic, A., Kunze, U. & Schäfer, T. Epidemiology of cutaneous melanoma and non-melanoma skin cancer in Schleswig-Holstein, Germany: incidence, clinical subtypes, tumour stages and localization (epidemiology of skin cancer). Br. J. Dermatol. 149, 1200–1206 (2003).
4. Ciazynska, M., Nartbutt, J., Wozniacka, A. & Lesiak, A. Trends in basal cell carcinoma incidence rates: a 16-year retrospective study of a population in central Poland. Adv. Dermatol. Allergol. 35, 47–52 (2018).
5. Malone, J. P., Fedok, F. G., Belchis, D. A. & Maloney, M. E. Basal cell carcinoma metastatic to the parotid: report of a new case and review of the literature. Ear Nose Throat J 79(511–515), 518–519 (2000).
Cited by
18 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献