No-reflow phenomenon following stroke recanalization therapy: Clinical assessment advances: A narrative review

Author:

Kan Yuan1,Li Sijie23,Zhang Bowei14,Ding Yuchuan5,Zhao Wenbo13,Ji Xunming6

Affiliation:

1. Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China

2. Department of Emergency, Xuanwu Hospital, Capital Medical University, Beijing, China

3. Beijing Key Laboratory of Hypoxia Conditioning Translational Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China

4. Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

5. Department of Neurosurgery, Wayne State University School of Medicine, Detroit, Michigan, USA

6. Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China

Abstract

The no-reflow phenomenon (NRP) after successful vascular recanalization in acute ischemic stroke (AIS) has become a major cause of poor clinical prognosis and ineffective recanalization. However, there is currently no clear definition or unified clinical assessment method for the NRP. Therefore, it is urgent to clarify the clinical evaluation criteria for the NRP and develop new no-reflow evaluation techniques so that remedial treatment can be applied to AIS patients suffering from the NRP. In this brief review, a variety of NRP assessment methods and defining criteria for clinical practice are presented.

Publisher

Medknow

Subject

General Economics, Econometrics and Finance

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