Metabolomic Analysis of Bone Morphogenetic Protein Receptor Type 2 Mutations in Human Pulmonary Endothelium Reveals Widespread Metabolic Reprogramming-Reference-Cited by-同舟云学术

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Metabolomic Analysis of Bone Morphogenetic Protein Receptor Type 2 Mutations in Human Pulmonary Endothelium Reveals Widespread Metabolic Reprogramming

Published:2012-04 Issue:2 Volume:2 Page:201-213
ISSN:2045-8940
Container-title:Pulmonary Circulation
language:en
Short-container-title:Pulm. circ.

Author:

Fessel Joshua P.¹,Hamid Rizwan²,Wittmann Bryan M.³,Robinson Linda J.¹,Blackwell Tom¹,Tada Yuji⁴,Tanabe Nobuhiro⁴,Tatsumi Koichiro⁴,Hemnes Anna R.¹,West James D.¹

Affiliation:

1. Department of MedicineDivision of AllergyPulmonary, and Critical Care MedicineVanderbilt UniversityNashvilleTennesseeUSA

2. Department of PediatricsVanderbilt UniversityNashvilleTennesseeUSA

3. MetabolonDurhamNorth CarolinaUSA

4. Department of Respirology (B2)Graduate School of MedicineChiba UniversityChibaJapan

Funder

National Center for Research Resources

National Institutes of Health

Publisher

Wiley

Subject

Pulmonary and Respiratory Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.4103/2045-8932.97606

Reference59 articles.

1. Primary pulmonary hypertension;Runo JR;Lancet,2003

2. Current therapeutics and practical management strategies for pulmonary arterial hypertension;Agarwal R;Am Heart J,2011

3. Molecular genetics and clinical features of Chinese IPAH and HPAH patients;Liu D;Eur Respir J,2012

4. Bone morphogenetic protein signalling in heritable versus idiopathic pulmonary hypertension;Dewachter L;Eur Respir J,2009

5. Idiopathic and heritable PAH perturb common molecular pathways, correlated with increased MSX1 expression;Austin ED;Pulm Circ,2011

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