Particle Image Velocimetry Tests on Pediatric 45-cc and 30-cc Ventricle Assist Devices: Effects of Heart Rate on VAD Operation

Abstract

Background This study investigated flow analysis inside pediatric ventricle assist devices (VADs) designed and manufactured at the Foundation for Cardiac Surgery Development (FRK), Zabrze, Poland. The main goal of the experiment was to define the minimal heart rate admissible in clinical practice. Methods The flow was directed by mechanical, single-disc valves developed at the Lodz University of Technology, Institute of Turbomachinery in Lodz, Poland. VAD operation conditions under different heart rates were analyzed. Measurements were performed on Religa PED pediatric VADs (45 cm3 and 30 cm3) with a particle image velocimetry (PIV) system. Results Due to the PIV method used, the measurements were made without interference of the measuring system onto the flow structure in the investigated channel, as the measurement procedure is noninvasive. During the investigations conducted in different measurement planes, the majority of the flow volume in the chamber was observable. Conclusions The measurements at different heart rates demonstrated a significant influence of this parameter on the flow nature in the heart ventricle. Additionally, it was found that the heart rate affected the operation of heart valves in the VAD.