Use of 18F-choline Positron Emission Tomography/CT in High-risk Prostate Cancer: a Case of Solitary Adrenal Metastasis

Author:

Matrone Fabio1,Sivolella Silvio2,Bellavita Rita3,Casciola Luciano4,Cristallini Enrico Giuseppe5,Aristei Cynthia6

Affiliation:

1. Radiation Oncology Section, University of Perugia, Perugia - Italy

2. Nuclear Medicine and PET Centre, San Giovanni Battista Hospital, Foligno - Italy

3. Radiation Oncology Division, Perugia General Hospital, Perugia - Italy

4. Department of Surgery, Division of General, Minimally Invasive and Robotic Surgery, San Matteo Hospital, Spoleto - Italy

5. Division of Pathological Anatomy, San Giovanni Battista Hospital, Foligno - Italy

6. Radiation Oncology Section, University of Perugia and Perugia General Hospital, Perugia - Italy

Abstract

Computed tomography and magnetic resonance imaging detected an isolated adrenal lesion in an elderly man with high-risk prostate cancer who was undergoing radiotherapy (RT) and hormonal therapy (HT). When prostate-specific antigen (PSA) was 31.66 ng/mL, the lesion was not identified as a metastasis by 18F-choline positron emission tomography/computed tomography (18F-choline-PET/CT). When PSA was over 100 ng/mL, 18F-choline-PET/CT diagnosed the malignancy. After adrenalectomy, PSA returned to normal, and stable disease remission was obtained. This case suggests that atypical metastasis may be underdiagnosed.

Publisher

SAGE Publications

Subject

Cancer Research,Oncology,General Medicine

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