Isolated Adrenal Metastases of Castration-Resistant Prostate Cancer-Reference-Cited by-同舟云学术

Isolated Adrenal Metastases of Castration-Resistant Prostate Cancer

Published:2023-11-22 Issue:1 Volume:49 Page:e8-e9
ISSN:1536-0229
Container-title:Clinical Nuclear Medicine
language:en
Short-container-title:Clin Nucl Med

Author:

Topal Edanur¹,Has Simsek Duygu¹,Vatansever Sezai²,Sanli Yasemin¹,Kuyumcu Serkan¹

Affiliation:

1. Department of Nuclear Medicine, Istanbul Faculty of Medicine

2. Department of Medical Oncology, Institute of Oncology, Istanbul University, Istanbul, Turkey.

Abstract

Abstract We present isolated bilateral adrenal metastases successfully treated with 177Lu-PSMA in a 66-year-old man diagnosed with castration-resistant prostate cancer. The patient had progression under chemotherapy as depicted by 68Ga-PSMA PET/CT showing intense bilateral PSMA uptake in the adrenal masses, and metastasis-directed therapies were considered as the first option for improving survival because the patient was oligometastatic. However, surgery and radiotherapy were not justifiable options due to the high risk of definitive adrenal insufficiency; therefore, the patient received 4 cycles of 177Lu-PSMA treatment. 68Ga-PSMA PET/CT showed near-complete response in bilateral adrenal metastases, and no sign of adrenal insufficiency was observed during follow-up.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Radiology, Nuclear Medicine and imaging,General Medicine

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