In vivo treatment with a subacute low dose of 3-nitropropionic acid does not induce genotoxicity or mutagenicity in rats
Author:
Funder
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Publisher
Elsevier BV
Subject
Toxicology
Reference28 articles.
1. Protective effect of minocycline, a semi-synthetic second-generation tetracycline against 3-nitropropionic acid (3-NP)-induced neurotoxicity;Ahuja;Toxicology,2008
2. Protective effects of chlorogenic acid in 3-nitropropionic acid induced toxicity and genotoxicity;Alarcón-Herrera;Food Chem. Toxicol.,2017
3. 3-Nitropropionic acid neurotoxicity is attenuated in copper/zinc superoxide dismutase transgenic mice;Beal;J. Neurochem.,1995
4. Mutant huntingtin in glial cells exacerbates neurological symptoms of Huntington disease mice;Bradford;J. Biol. Chem.,2010
5. Profilin-2 increased expression and its altered interaction with β-actin in the striatum of 3-nitropropionic acid-induced Huntington's disease in rats;Chakraborty;Neuroscience,2014
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2. An Overview of the Pathophysiological Mechanisms of 3-Nitropropionic Acid (3-NPA) as a Neurotoxin in a Huntington's Disease Model and Its Relevance to Drug Discovery and Development;Neurochemical Research;2023-02-04
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