An Overview of the Pathophysiological Mechanisms of 3-Nitropropionic Acid (3-NPA) as a Neurotoxin in a Huntington's Disease Model and Its Relevance to Drug Discovery and Development-Reference-Cited by-同舟云学术

An Overview of the Pathophysiological Mechanisms of 3-Nitropropionic Acid (3-NPA) as a Neurotoxin in a Huntington's Disease Model and Its Relevance to Drug Discovery and Development

Published:2023-02-04 Issue:6 Volume:48 Page:1631-1647
ISSN:0364-3190
Container-title:Neurochemical Research
language:en
Short-container-title:Neurochem Res

Author:

Upadhayay Shubham,Yedke Narhari Gangaram,Rahi Vikrant,Singh Surbhi,Kumar Sachin,Arora Anchal,Chandolia Priyanka,Kaur Prabhsharan,Kumar Mandeep,Koshal Prashant,Jamwal Sumit,Kumar Puneet

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,General Medicine,Biochemistry

Link

https://link.springer.com/content/pdf/10.1007/s11064-023-03868-1.pdf

Reference170 articles.

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3. Herrera-Mundo N, Sitges M (2013) Vinpocetine and α-tocopherol prevent the increase in DA and oxidative stress induced by 3-NPA in striatum isolated nerve endings. J Neurochem 124(2):233–240

4. Silva-Palacios A et al (2017) 3-NP-induced Huntington’s-like disease impairs Nrf2 activation without loss of cardiac function in aged rats. Exp Gerontol 96:89–98

5. Gu M et al (1996) Mitochondrial defect in Huntington’s disease caudate nucleus. Ann Neurol 39(3):385–389

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