Identification of novel B-RafV600E inhibitors employing FBDD strategy-Reference-Cited by-同舟云学术

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Identification of novel B-RafV600E inhibitors employing FBDD strategy

Published:2017-05 Issue: Volume:132 Page:63-76
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Wang Peng-Fei,Qiu Han-Yue,Wang Ze-Feng,Zhang Yong-Jiao,Wang Zhong-Chang,Li Dong-Dong,Zhu Hai-Liang

Funder

Public Science and Technology Research Funds Projects of Ocean of China

Guangxi University for Nationalities

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference22 articles.

1. Mitogen-activated protein kinases and their role in radiation response;Munshi;Genes & Cancer,2013

2. Design, biological evaluation and 3D QSAR studies of novel dioxin-containing triaryl pyrazoline derivatives as potential B-Raf inhibitors;Yang;Bioorg. Med. Chem.,2016

3. Identification of BRAF inhibitors through in silico screening;Luo;J. Med. Chem.,2008

4. Discovery of 1-(3, 3-Dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino) pyrido [2, 3-d] pyrimidin-6-yl) phenyl) urea (LY3009120) as a Pan-RAF Inhibitor with Minimal Paradoxical Activation and Activity against BRAF or RAS Mutant Tumor Cells;Henry;J. Med. Chem.,2015

5. Targeting RAF kinases for cancer therapy: BRAF mutated melanoma and beyond;Holderfield;Nat. Rev. Cancer,2014

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