Identification of BRAF Inhibitors through In Silico Screening
Author:
Affiliation:
1. The Wistar Institute and Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm800539g
Reference18 articles.
1. Raf kinase as a target for anticancer therapeutics
2. Guilty as charged
3. Mechanism of Activation of the RAF-ERK Signaling Pathway by Oncogenic Mutations of B-RAF
4. Kinase Inhibition with BAY 43–9006 in Renal Cell Carcinoma
5. Discovery of a Potent and Selective Protein Kinase CK2 Inhibitor by High-Throughput Docking
Cited by 43 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. KinomeMETA: meta-learning enhanced kinome-wide polypharmacology profiling;Briefings in Bioinformatics;2023-11-22
2. A novel phosphorylation site involved in dissociating RAF kinase from the scaffolding protein 14-3-3 and disrupting RAF dimerization;Journal of Biological Chemistry;2023-10
3. Molecular Docking Studies for Evaluation of Amaranth Grain Squalene for Treatment of Melanoma Skin Cancer in Human Beings;Letters in Organic Chemistry;2023-09
4. Molecular Modeling Unveils the Effective Interaction of B-RAF Inhibitors with Rare B-RAF Insertion Variants;International Journal of Molecular Sciences;2023-07-31
5. Computational investigation of imidazo[2,1-b]oxazole derivatives as potential mutant BRAF kinase inhibitors: 3D-QSAR, molecular docking, molecular dynamics simulation, and ADMETox studies;Journal of Biomolecular Structure and Dynamics;2023-07-09
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3