Application and interpretation of hPXR screening data: Validation of reporter signal requirements for prediction of clinically relevant CYP3A4 inducers

Author:

Cui Xiaoming,Thomas Ann,Gerlach Valerie,White Ronald E.,Morrison Richard A.,Cheng K.-C.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference70 articles.

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3. CYP3A4 induction by xenobiotics: biochemistry, experimental methods and impact on drug discovery and development;Luo;Curr Drug Metab,2004

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5. Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction;Bertilsson;Proc Natl Acad Sci USA,1998

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